The 2026 threat landscape has moved past simple data theft into a new era of Operational Erasure, where state-sponsored actors and AI-augmented groups target the virtualization layers of critical infrastructure. For critical infrastructure, a cyber event isn't just a data leak—it's a potential halt to global supply chains and smart-access ecosystems. This panel explores the shift from static defense to dynamic resilience, discussing how AI is being leveraged to build self-healing infrastructure and how the CISO's role has evolved into a "Chief Resilience Officer." We will dive into the hard-won lessons of 2025, the reality of managing AI-driven Agentic threats, and why recovery preparedness is now more valuable than the perimeter itself.